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Tate, P.S., Freed, D.M., Bombardier, C.H., Harter, S.L., & Brinkman S. (1999). Traumatic brain injury: Influence of blood alcohol level on post-acute cognitive function. Brain Injury, 13,767-784.
 
Type of 
Study
Research Study
Subjects
  • 143 subjects between the ages of 16-65 
  • ratio of male to female patients was 2.19 :1
  • 76.1% European American, 13.4% Mexican American, 7.5% African American, 3% Native American
Diagnosis
Closed head injury
Purpose
Examine whether acute pre-injury alcohol intoxication or premorbid history of alcohol abuse impacts cognitive functioning during the post-acute stage of recovery from traumatic brain injury (TBI).
Methods
Neuropsychological test files and medical charts and were researched to compile information on: recent history of alcohol abuse, measures of TBI severity, etiology of injury, neuropsychological  test data,  BAL (blood alcohol level) , and the amount of time between injury and neuropsychological evaluation.  Demographic information including age, ethnicity, years of education , and gender  was also collected.
Results
  • Higher BAL correlated with poorer performance on many neuropsychological measures during the post -acute stage of recovery. 
  • In a sample of adults with mild to severe closed head injury , higher BAL correlated with poorer delayed recall for prose material (WMS-R Logical Memory 2), greater decrement of verbal memory between test trials (WMS-R Logical Memory Residual), and poor performance on a measure of planning, organization, and visuospatial ability (WAIS-R Block Design).
Treatment Implications
  • Patients who are intoxicated at the time of TBI and are referred for cognitive  rehabilitation following TBI should be evaluated for history of alcohol abuse by professionals. 
  • Therapy should target memory, spatial functioning, and conceptual flexibility. 
  • Timely assessment and intervention in therapy setting may reduce the amount of alcohol abuse that typically occurs following TBI.
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