McCabe, C.F. & Donahue, S.P.  (2000).  Prognostic indicators for vision and mortality in shaken baby syndrome. Arch Opthalmol, 118, 373-377.
Objective To study ocular and nonocular signs of patients diagnosed as having "shaken baby syndrome" and determine prognostic indicators for vision and mortality.
Methods Researchers reviewed the medical charts of child abuse cases involving bilateral retinal hemorrhages.  They paid particular attention to visual function and pupillary light reaction at the time of admission as well as the location of the retinal hemorrhage, neuroimaging findings, ventilatory requirement and associated skeletal injuries.  The information was obtained from the charts was compared with visual prognosis and mortality.
Results There were thirty cases that met the criteria for review.  On the first visit the mean age of the children was 9.3 months and 12 (40%) children had at least fix-and-follow vision.  The researchers found that preretinal and intraretinal hemorrhages were more common (93% [n=28] and 100% [n=30]), respectively  than vitreous hemorrhages (10% [n=3]).  Subdural hematomas were detected in 21 patients (70%).  There were 20 children (67%) who had seizures and 16 (53%) required ventilators.  There were bruises and long bone fractures found in 14 (47%).  Eight  patients died.  All patients with nonreactive pupils on initial visit died, while patients with a pupillary light reaction lived.  Six (86%) of 7 patients with midline shift post trauma died, whereas 21 (91%) of 23 with no midline shift lived.  At the follow-up, retinal hemorrhages had resolved in nearly all children by 4 months, and 16 children (73%) had at least fix-and-follow vision.  A correlation was found between the need for ventilator support and poor vision. 
 Conclusion
 Nonreactive pupils and midline shift of the brain structures correlate highly with mortality.  Ventilatory requirement, but not visual acuity on presentation, predicts visual outcome. 

 
 
 
 
 
 
 

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